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Sativex (Nabiximols)


Sativex (nabiximols) is the first cannabis-based medicine to be licensed in the UK. The drug can prescribed for the treatment for MS-related spasticity when a person has shown inadequate response to other symptomatic treatments or found their side effects intolerable. Sativex can be used in addition to a person’s current anti-spasticity medication.

Prior to gaining a licence for use in MS-related spasticity, Sativex had been studied for its effects on a number of MS related symptoms including: spasticity and spasms, pain, bladder symptoms, tremor, and sleep disturbance.

What Is Sativex? And How Is It Different from Marijuana?

Sativex is the very pharma-sounding marijuana-based patented pharmaceutical that has been approved in over 24 countries and counting.

Available as a peppermint-flavored mouth spray, it is the first pharmaceutical drug of its kind. It is currently being prescribed as a method of coping for patients with MS (multiple sclerosis) in countries such as the United Kingdom, Spain, Australia, and Canada. It could be approved for use in the United States too.

This article will seek to answer the question, “what is Sativex?” It will touch upon how it’s made and try to clear up just how the legality of this marijuana-extract actually differs from the still-illegal-in-the-USA marijuana.

Side effects of Sativex and contraindications

Sativex is created using cannabis, and while the aforementioned ratio of THC to CBD can be lower than other, more potent strains of cannabis, it can still produce a high similar to that of smoking marijuana. Common side effects include dizziness, drowsiness, diarrhoea, fatigue, nausea, headache and a dry mouth. It is not recommended for pregnant women and people under 18 years old. People with a history of psychotic problems should not take the drug.

Sativex may impair the mental and/or physical abilities required for certain potentially hazardous activities such as driving a car. People who experience any significant side effects should not drive, operate machinery or take part in any activity that could prove hazardous.

Medical marijuana users are now often quite savvy in avoiding the negative effects of smoking in general, opting for vaporizers to circumvent issues of oral discomfort. This isn’t the case for a portion of this users, who have reported oral discomfort after administering the mouth spray.

Although the compounds are similar, it’s the method of consumption and levels of standardization that marks Sativex out as different from medical marijuana.


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